Edworthy, S. M. and G. M. Devins (1999). "Improving medication adherence through patient education distinguishing between appropriate and inappropriate utilization. Patient Education Study Group. ." Journal of Rheumatology 26(8): 1793-801.

"…computer assisted education focusing on appropriate vs inappropriate continuation and discontinuation of medications has the potential to improve knowledge, increase self-efficacy, maintain realistic expectations, and facilitate adherence, resulting in more beneficial clinical outcomes."

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Krishna, S., E. A. Balas, et al. (1997). "Clinical trials of interactive computerized patient education: implications for family practice." Journal of Family Practice 45(1): 25-33.

"A systematic review of randomized clinical trials was conducted to evaluate the acceptability and usefulness of computerized patient education interventions...Computerized educational interventions can lead to improved health status in several major areas of care, and appear not to be a substitute for, but a valuable supplement to, face-to-face time with physicians."

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Leirer, V. O., D. G. Morrow, et al. (1988). "Elders' nonadherence, its assessment, and computer assisted instruction for medication recall training." Journal of the American Geriatrics Society 36(10): 877-84.

"Results of the present study suggest that physically active and cognitively alert elders do have significant nonadherence (control group = 32%) problems related to forgetting and that CAI courseware can significantly reduce (medication recall training group = 10%) this form of nonadherence."

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Lewis, D. (1999). "Computer-based approaches to patient education: a review of the literature. [Review] [68 refs]." Journal of the American Medical Informatics Association 6(4): 272-82.

"… eight authors [out of 13] reported that knowledge presented by computer-based patient education methods resulted in improved clinical outcomes when compared with traditional patient education methods [the other 5 studies showed equal gains]."

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Shaw, M. J., T. J. Beebe, et al. (2001). "A randomized, controlled trial of interactive, multimedia software for patient colonoscopy education." Journal of Clinical Gastroenterology 32(2): 142-7.

"The largest effect of CAI was in recognizing the first signs of serious complications: participants were more than three times more likely to recognize these signs."

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